The Mongan Institute's research centers and programs incorporate a wide array of methods to solve the most challenging and complex problems in health care. Examples include clinical translational epidemiology, data science, predictive modeling, cost-effectiveness analysis, decision science, health disparity research, health policy, health behavior, survey research, outcomes research, intervention trials, and implementation research.


Each center is an established leader in its field and is committed to transforming health care and advancing health equity for people with complex needs, and training the next generation of leaders in population and health care science. In addition to supporting research by core Mongan faculty, The Mongan Institute supports affiliated researchers and teams in the Department of Medicine and across clinical departments at the Massachusetts General Hospital.


Research at The Mongan Institute

Mongan Institute colleagues listening during a meeting


Biostatistics & Data Science Unit

The Biostatistics and Data Science Unit engages in transdisciplinary collaborations involving the development, application, and evaluation of leading-edge biostatistical methods and data science tools.


Cancer Outcomes Research and Education Program

CORE conducts innovative research and educational programs to improve the experience and outcomes of patients and caregivers across the continuum of cancer care.


Center for Aging & Serious Illness

The Center for Aging and Serious Illness is a new research center established in the fall of 2019 that brings together researchers across MGH and the Boston community to improve the well-being of older adults and enhance the lived experience of those with advanced illnesses.


Center for Primary Care Research

Researchers in the Center for Primary Care Research focus on a full range of topics from preventive medicine and population health to improving patient care and managing chronic disease.


Clinical & Translational Epidemiology Unit

The CTEU advances the translation of discoveries into effective clinical interventions in chronic disease through epidemiologic investigation.

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Disparities Research Unit

The Disparities Research Unit is dedicated to the exploration of imbalances in health care treatment, generating innovative health services research that impacts policy, practice, and service delivery for multicultural populations.


Disparities Solutions Center

The DSC is dedicated to the development and implementation of strategies that advance policy and practice to improve quality, eliminate racial and ethnic disparities, and achieve equity in health care in a time of rapid transformation.

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Health Decision Sciences Center

The HDSC is a multidisciplinary research group that seeks to foster shared decision making and implement sustainable decision aid delivery. The HDSC is committed to improving the quality of decisions made by patients and health care providers from diagnosis through treatment.

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Health Policy Research Center

The HPRC aims to catalyze beneficial changes in health policy, the health and care of marginalized populations, and the health care delivery system.

  • Twitter @MonganHealthPol


Health Promotion and Resiliency Intervention Research Program


This joint initiative between the Mass General Mongan Institute Health Policy Research Center and the Mass General Department of Psychiatry  harnesses the strengths of interdisciplinary behavioral health services research to advance resiliency delivery science to promote health and wellness.

  • Twitter @MGH_HPRIR


Medical Practice Evaluation Center

MPEC works to improve clinical outcomes, increase value in health policy, and inform global public health through innovative research, collaboration, and education.​

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Rheumatology, Allergy, & Immunology Clinical Epidemiology Program

The Clinical Epidemiology Program of the Division of Rheumatology, Allergy, and Immunology conducts research related to allergic and rheumatologic diseases using clinical research methods that include advanced informatics, clinical epidemiology, primary data collection, and simulation science.

  • Twitter @MGH_ClinEpi


Tobacco Research & Treatment Center

The Tobacco Research & Treatment Center reduces the toll of tobacco-related disease by identifying innovative tobacco cessation treatments, promoting the delivery of effective treatment in the health care delivery system, and evaluating the impact of tobacco control public policies.